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It was simple, but a physician-led, not-for-profit medical system was unique in 1921 when Cleveland Clinic was established.

Our founders envisioned a future where physicians could share their clinical expertise and devote themselves to educating new generations of caregivers, and where applied research would lead to groundbreaking innovations in healthcare.

Provide better care of the sick, investigation into their problems, and further education of those who serve."

- Our Founder’s Mission Statement

Our Breakthroughs

Every year, we want to push the boundaries of care by investing in research and improving our institute model of medicine to ensure that we are matching the right resources with the best practices. We pride ourselves on the many medical breakthroughs and firsts that occur in our facilities.

Our timeline of Breakthroughs

1921 Cleveland Clinic was founded.

1940s The isolation of serotonin, a key factor in hypertension, is discovered.

1958 The first coronary angiography is developed.

1967 The development and refinement of coronary bypass surgery is pioneered.

1996 The first minimally invasive aortic heart valve surgery is developed.

1998 The first successful larynx transplant is completed.

1999 Lerner Research Institute opens. 

2004 Toby Cosgrove, MD, is appointed CEO and President.

2006 Pioneering success in deep brain stimulation for psychiatric disorders is achieved.

2007 The first kidney surgery through a patient’s navel is performed.

2008 The nation’s first near-total face transplant is completed.

2011 The nation’s first transcatheter valve replacement and repair is achieved.

2011 The discovery that adult brain neurons can regenerate is made.

2012 Bariatric surgery as an effective treatment for diabetes is demonstrated.

2013 The intestinal bacteria product TMAO’s ability to predict heart disease risk is discovered.

2015 The first fMRI-guided deep-brain stimulation is completed.

Cleveland Main Campus Integrated approach

An Integrated Approach

Cleveland Clinic is a future-focused model for healthcare. It is not enough to react to our current reality, but rather we must continually invest in identifying macro trends and developing targeted solutions.

Cleveland Main Campus Core Values

Our Core Values

With patient care at the center of everything we do, we continually look for new, innovative ways to improve outcomes and experiences for our patients and their families.

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